What is the appropriate dose of ketamine used for sedation?

The appropriate dose of ketamine for sedation is generally around 1 to 2 mg/kg when administered intravenously. In some contexts, particularly in emergency settings or when deep sedation is required, doses can be increased. The choice of 4 mg/kg may be appropriate in certain scenarios, such as when a patient requires a higher level of sedation, allowing for deeper analgesia and dissociative effects, which are characteristic of ketamine use. This dosing leverages ketamine’s rapid onset and relatively favorable safety profile, making it effective for procedures that may cause significant discomfort or anxiety.

Considering the context of sedation, it is essential to individualize dosing based on patient factors, procedural needs, and desired depth of sedation. Normal practice usually wouldn't go beyond 4 mg/kg under typical sedation circumstances.